We ask patients to set goals when their prognosis is short. This is necessary work that helps patients to prioritize. But do we diminish joy-of-life events by making explicit that this marriage, graduation, or baby might be the very last one? https://ja.ma/2OcznYC
In new letter just posted, Gilead CEO says the company has ramped up remdesivir supply to 1.5 million individual doses (depending on optimal duration of treatment, which is being studied, could equate to 140K+ courses) which it’s providing to treat severe #COVID19 at no cost (1)
New pediatric #migraine guidelines recommend acute and preventive treatments. JAMA Neuro synopsis highlights strengths, areas for future research. https://ja.ma/2vQKbWp
A 31-year-old woman presented with blurred vision and proptosis of the left eye. An MRI revealed a retrobulbar cystic lesion, which was confirmed on histopathological examination to be a hydatid cyst.
#ONCHighlights from the #JAMANetwork https://ja.ma/2X9DdHp
Patients with mantle-cell lymphoma who have a relapse after chemotherapy and anti-CD20 and BTK inhibitor therapy have a poor prognosis. An injection of CD19-directed CAR T cells induced a complete response in 59% of patients, with 78% of these patients in remission at 1 year.
#Casereport: a woman in her 30s with a jellyfish sting on her right wrist, which caused erythematous serpiginous plaques with superficial scaling in a braceletlike shape https://ja.ma/33bdNdl
Study adds to the growing evidence of the need for long-term follow-up for all children with #Zikavirus exposure in utero https://ja.ma/32HqFaQ
Systematic review & meta-analysis finds a high burden of STIs among #HIV #PrEP users; underscores the need for comprehensive sexual health services. https://ja.ma/3aVrmB5
Fascinating article from pediatric emergency doc @drsujitsharma about social/physical distancing during and after an ice storm. Back then, everyone was stuck at home and look what happened.
Thank you, @CNNOpinion! We need hope...light at end of this endless tunnel. TY @drsanjaygupta, for being an inspiring voice for all healthcare workers...leading by example: providing people hope, with data rather diatribe. @AnnChahroudi @LoraxMD https://twitter.com/CNNOpinion/status/1246269441848950784?s=20
In-hospital mortality after acute upper GI bleeding has been estimated at 10%. Endoscopy, which allows identification of the source of bleeding, is recommended within 24 hours after consultation; whether earlier endoscopy would reduce mortality has not been known.
Felt very luck to catch up with @davidaxelrod for the #AxeFiles. Felt like two friends just catching up. No agenda. No hurry. Just real conversation. With everyone staying at home, I encourage you to do the same. Good for the mind and the soul. Thanks David.
Today, @drsanjaygupta is a trusted and comforting source for Americans in a time of crisis. But on latest #AxeFiles, he speaks movingly about his struggle to find belonging as a young Indian-American in a homogenous suburban community.
Here’s full pod👇
https://cnn.com/axefiles
This article provides U.S. national estimates for 6 common nosocomial pathogens: MRSA, vancomycin-resistant enterococcus, carbapenem-resistant acinetobacter species, multidrug-resistant P. aeruginosa, carbapenem-resistant Enterobacteriaceae, and ESBL-producing Enterobacteriaceae.
This interactive graphic provides a guide to the history, epidemiology, and clinical characteristics of tuberculosis and highlights the obstacles to and strategies for containing infection.
Frontal and temporal brain development (girls) and impulsivity (boys) promote moderate frequency of drunkenness increase during adolescence. https://ja.ma/2V3Un6o
I fear caring for patients with #COVID19 because I fear my own risk, and a role wrapped in fear seems less wanted, less chosen #medhum https://ja.ma/2X4p2mG
Quality versus quantity: lets identify the how, when, and why of pediatric #palliativecare https://ja.ma/2R2s8nG
Case report: a 20-year-old man with a 1-month history of skin induration and a prominent groove sign along the course of the forearm vein https://ja.ma/2JwitBw
In the absence of tumor rupture, microscopic margins status does not seem to impact OS and RFS in localized GIST with or without adjuvant Imatinib. https://ja.ma/3bG5AAS
#RelativeSurvival rates >100% in early-stage cancers of the #breast, #thyroid, #prostate and #melanoma can help frame patient discussions on prognosis https://ja.ma/2IeOu09
"Ultrasonography is a relatively inexpensive and widely available imaging modality and therefore should be the first line for the diagnosis of PAS disorders:"
http://ow.ly/ICIS50vDj5O
#MostCited https://obgyn.onlinelibrary.wiley.com/doi/10.1002/ijgo.12408
Patients with acute upper gastrointestinal bleeding were assigned to receive endoscopy within 6 hours or between 6 and 24 hours after gastroenterological consultation. Earlier endoscopy did not lower mortality.
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#ONCHighlights from the #JAMANetwork https://ja.ma/2yyTrzu
https://ja.ma/3dWLQL4 From @JAMANetwork #mostcited
https://ja.ma/347tyT6
#Migraine and #IschemicStroke in Women: A Narrative Review
Gretchen Tietjen and @EmilyMaly4
https://headachejournal.onlinelibrary.wiley.com/doi/10.1111/head.13796
As a resource to the global health care community, the NEJM collection of Covid-19 articles continues to be free. #COVID19 #SARSCoV2
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