In this stepped-wedge, cluster RCT, among infants and children anticipated to require prolonged mechanical ventilation, a sedation & ventilator liberation protocol intervention resulted in a reduction in time to first successful extubation https://ja.ma/3A7YfGm
In this stepped-wedge, cluster RCT, among infants and children anticipated to require prolonged mechanical ventilation, a sedation & ventilator liberation protocol intervention resulted in a reduction in time to first successful extubation https://ja.ma/3rOLptT
In this stepped-wedge, cluster RCT, among infants and children anticipated to require prolonged mechanical ventilation, a sedation & ventilator liberation protocol intervention resulted in a reduction in time to first successful extubation https://ja.ma/3fqI9zZ
A 41-year-old woman with presumed Alport’s syndrome was admitted with bloody stools and rectal pain. Six months earlier, she had a deceaseddonor renal transplantation. On admission, blood pressure was 85/46 mm Hg, hemoglobin level 6 g per deciliter, and platelet count 0 per μL.
High-risk-HPV positivity during long-term follow up is a risk factor for high-grade disease recurrence after cervical excisional treatment in women living with HIV: http://ow.ly/COTZ50FH3xy
Veerasingham will be 1st woman, 1st person of color and 1st from outside the US to lead the AP in its 175-year history. She said she's determined to maintain the AP as a source of fact-based, nonpartisan journalism, and to fight for freedom of the press and access to information.
Daisy Veerasingham named president and CEO of The Associated Press: http://apne.ws/7FNrScX
Depression in adolescents is increasing at a greater rate than in adults. Change in appetite, loss of energy, and insomnia may be more apparent than mood changes. Pharmacologic treatment and psychotherapy are effective, but stigma and medication adverse effects impede treatment.
All NEJM articles on the Race and Medicine topic page are freely available.
There's a direct correlation between #covid19 vaccine cvg and case rates, @CDCDirector says. Sadly, delta's impact isn't limited to case increases: Florida is seeing record hospitalizations. But number of people seeking out vaccines is ticking up, particularly in hard-hit states.
80% of all U.S. counties have high or substantial Covid transmission levels, the CDC says. @megtirrell has the details. https://cnb.cx/3ikJWYW
A clinical trial assessed the efficacy of three treatments, all involving metformin, on glycemic control in youth-onset type 2 diabetes. This follow-up study shows that the risk of complications increased steadily over time.
Great story from @rachelcohrs @statnews. We know some folks are seeking out third #covid19 vaccine doses. How are healthcare systems, insurers & the @CDCgov handling them? https://www.statnews.com/2021/08/03/people-chasing-covid-19-vaccine-boosters-create-headaches-for-the-health-care-system/
Saw this first without the sound on and was concerned I was popping up as a bad example of something
For all the people in your life who bathe in misinformation about COVID & Delta, here's a reassuring breakdown of what you need to know from the good Dr. @ashishkjha (who did not get his medical degree from Google University).
https://crooked.com/podcast/the-fear-olympics/
McDonald’s says it will require employees and customers to resume wearing masks inside some U.S. restaurants regardless of vaccination status. The company said Monday that the mandate will apply in areas with high or substantial coronavirus transmission.
The Latest: Famed Minneapolis club requiring vaccination
MINNEAPOLIS — The First Avenue music venue in Minneapolis that was made famous in Prince’s movie “Purple...
apnews.com
A federal appeals court ruled Monday that Indiana University can proceed with its plan to require students and employees to get vaccinated for COVID-19, in what is the highest court decision regarding college immunization mandates.
Indiana University giving students option on vaccine proof
INDIANAPOLIS (AP) — Indiana University modified its COVID-19 vaccination requirement on Tuesday, making it optional th...
apnews.com
Senator @LindseyGrahamSC reports he has #covid19, notes he feels vaccine is protecting him from severest effects:
I feel like I have a sinus infection and at present time I have mild symptoms.
I will be quarantining for ten days.
I am very glad I was vaccinated because without vaccination I am certain I would not feel as well as I do now.
My symptoms would be far worse.
UK planning boosters 👇
Germany too: https://www.nytimes.com/live/2021/08/02/world/covid-delta-variant-vaccine/germany-plans-to-offer-vaccine-booster-shots-starting-in-september
Vaccine booster shots for 32m to begin next month in UK https://www.telegraph.co.uk/politics/2021/08/01/vaccine-booster-shots-32m-begin-next-month/
How the Earth's oxygen surge, and life as we know it, may have begun. Expertly explained by @borenbears who knows how to spot a cool study.
Scientists propose that longer daylight kick-started weird bacteria into producing lots of oxygen, making most of life as we know it possible on Earth.
http://apne.ws/Xy6AXE4
70% of US adults have now had at least 1 dose of #covid19 vaccine 👇 (initial goal was July 4)
Milestone Monday just in: Today we hit 70% of adults w/ at least one dose! +468K doses reported administered, incl. 320K newly vaccinated (vs. 257K last Monday). 7-day average of newly vaccinated highest since July 4. Let's continue working to get more eligible vaccinated! 🇺🇸
AI-based app provides evidence-based #self-management support and improves #lowbackpain disability when added to usual care https://ja.ma/3C5u4Bv
ANGIOCAT clinical trial: Direct transfer to angiography suite increased the odds of undergoing EVT, reduced hospital workflow time and improved clinical outcome among patients with large vessel occlusion admitted in early window https://ja.ma/3xpONg4
Congenital cytomegalovirus infection is a cause of serious perinatal complications. In this randomized trial involving 399 pregnant women, CMV hyperimmune globulin was found to provide no benefit with respect to congenital CMV infection or perinatal death.
ANGIOCAT clinical trial: Direct transfer to angiography suite increased the odds of undergoing EVT, reduced hospital workflow time and improved clinical outcome among patients with large vessel occlusion admitted in early window https://ja.ma/3ll22w3
AI-based app provides evidence-based #self-management support and improves #lowbackpain disability when added to usual care https://ja.ma/3xhdXx1
C. difficile detected in over 40% of asymptomatic children 6 to 12 months of age and even 12% of children 5 to 18 years and differs based on geographic region, and testing method. Interpret C. difficile positive tests in children with caution https://ja.ma/3fiyM5h
AI-based app provides evidence-based #self-management support and improves #lowbackpain disability when added to usual care https://ja.ma/3yjw72N
ANGIOCAT clinical trial: Direct transfer to angiography suite increased the odds of undergoing EVT, reduced hospital workflow time and improved clinical outcome among patients with large vessel occlusion admitted in early window https://ja.ma/2VuT04Q
Cohort study of measured coronary artery calcium (CAC) on radiotherapy planning CT imaging for breast cancer shows an assoc'n between CAC & cardiovascular disease (CVD), particularly in pts treated w/anthracyclines & those who received a radiation boost https://ja.ma/3kh8uUi
In a cross-sectional study, US Black women who experienced racial discrimination showed increased functional MRI response in brain regions associated with emotion regulation and fear inhibition and visual attention https://ja.ma/3zKKmhj
Study suggests that granuloma annulare is a rare disease in the United States that predominantly affects women and middle-aged to older individuals https://ja.ma/3rnKd08
The sequencing and choice of cancer-directed treatments in resectable PDAC patients has been a subject of heated debate. This up-to-date review highlights methodological aspects of the resectable PDAC trials and analyzes their results under a new light https://ja.ma/2Ue7Ufc
Policymakers are moving forward with payment models that establish budgets for rural health care organizations. Such programs reflect an attempt to help remedy what ails rural health care: insufficient investment, high costs, and unstable and decreasing patient volume.
Women who gave birth during the pandemic had higher scores for somatization, obsessions and compulsions, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, and psychoticism: http://ow.ly/CiAb50FH2Pj
#TrendingArticle
Tens of thousands of people in New Mexico who are behind on their gas and electric bills could lose power as soon as mid-August after a pandemic moratorium on utility shutoffs ended. https://apnews.com/article/business-health-new-mexico-coronavirus-pandemic-bills-975eac79ba4841a97e39d70227e7cfa4
Evictions, which have mostly been on pause during the pandemic, were expected to ramp up Monday after the Biden administration allowed the federal moratorium to expire over the weekend and Congress was unable to do anything to extend it. https://apnews.com/article/evictions-moratorium-ends-pandemic-5ea6a36efe4e5e7d169fcefbd1dd298a
In the @NEJM Covid-19 Vaccine Resource Center, @PaulSaxMD provides concise and engaging answers to clinicians’ questions about Covid-19 vaccination and to the questions and concerns patients will raise. #SARSCoV2 #IDTwitter
A 12-year-old boy presented with a 4-day history of sore throat and dark urine. He was found to have jaundice with an icteric tongue, and the hemoglobin level was 6.1 g per deciliter. A diagnosis of cold agglutinin, EBV-induced acute hemolytic anemia was made.
.@Laurie_Garrett includes an interesting hypothesis in this piece (mainly about need for boosters) on why UK cases peaked so quickly: wider spacing of vaccine doses
Thanks @CapehartJ & @MSNBC for giving me a chance this AM to explain what I wrote in @ForeignPolicy : why the #DeltaVariant is so dangerous, and means that everybody -- including fully vaccinated individuals -- needs to mask-up to stop spread of #COVID19 .
https://foreignpolicy.com/2021/07/30/booster-shot-coronavirus-covid-science/
In this editorial, Pamela J. Goodwin, M.D., discussed the final results of the phase 3 Austrian Breast and Colorectal Cancer Study Group Trial 16, a study of aromatase inhibitors involving 3,486 postmenopausal women with hormone-receptor–positive breast cancer.
The modified definition provided a more consistent estimate of near-miss incidence and mortality index. Lowering the threshold for units of blood transfusion might improve comparability between settings, but more research is needed: http://ow.ly/kqe850FH39C
The NEJM Clinical Cases Resource Center aggregates interactive cases and educational resources developed specifically for teaching, continuous learning, and professional development.
CDC Director doesn’t appear to be making Sunday news show rounds this weekend: https://www.politico.com/news/2021/07/31/the-shows-sunday-listings-for-aug-1-2021-501930
Despite improvements resulting from the use of adjuvant endocrine therapy and aromatase inhibitors in luminal breast cancer, the risk of recurrence continues, with more than half diagnosed after the first 5 years. New research findings are summarized in a short video.
Covid-19 Rx: Your task is to gather data, develop a differential diagnosis, order additional diagnostic tests, and treat the patient. (Optimized for desktop PCs and most tablets.) #COVID19
With the increase in obesity prevalence among women of reproductive age globally, the risks of type 2 diabetes, gestational diabetes, pre-eclampsia, and other conditions are rising, with detrimental effects on maternal and newborn health: http://ow.ly/2mML50FH35A
Nathaniel Morris, M.D., discusses the role of clinicians in programs that provide alternatives to incarceration.
A 42-year-old woman receiving induction chemotherapy for acute monocytic leukemia developed edematous, erythematous plaques on her face. Biopsy showed perieccrine neutrophilic infiltration with eccrine duct necrosis. What is the most likely diagnosis?
.@CDCDirector clarifies comments made to Fox News earlier. Asked by @BretBaier "Are you for mandating the vaccine on a federal level?" Dr Walensky said: "That's something that I think the administration is looking into." She says she meant portions of federal govt:
@BerkeleyJr .@BerkeleyJr To clarify: There will be no nationwide mandate. I was referring to mandates by private institutions and portions of the federal government. There will be no federal mandate.
Open Access:
Efficacy & safety of #fremanezumab for #chronicmigraine prevention: Multicenter, randomized, double-blind, placebo-controlled, parallel-group trial in Japanese & Korean patients
Fumihiko Sakai MD PhD et al
#migraine
#CGRP
https://headachejournal.onlinelibrary.wiley.com/doi/full/10.1111/head.14169
Efficacy of a pediatric #headache infusion center: A single-center experience
Gogi Kumar MD FAES, Asia M Payne MS, MSIV, Logan Mark Maag MD, Sarah MacDonald MSN RN CPN @DaytonChildrens
https://headachejournal.onlinelibrary.wiley.com/doi/full/10.1111/head.14173
